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Anti-Bax Rabbit mAb [59M52K38]

Purified Rabbit Monoclonal Antibody

货号 规格 价格
R013644
100µL ¥1780.00
50µL ¥1080.00
20µL ¥588.00

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Bax antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Bax in C6, 3T3, Hela lysates using Bax antibody.

Product Name Anti-Bax Rabbit mAb
Description Purified Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IP, ELISA
Dilution WB 1:500~1:1,000; IHC-P 1:50~1:100; IP 1:20
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Clone No. 59M52K38
Isotype IgG
Target / Specificity A synthetic peptide of human Bax
Format Buffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified.
Gene ID 581
Other Names Apoptosis regulator BAX, BAX, Bcl-2-like protein 4, BCL2-associated X protein, Bcl2-L-4, BCL2L4.
Calculated MW Calculated MW: 21 kDa; Observed MW: 21 kDa
Primary Accession Q07812
Storage Shipped at 4℃. Upon delivery aliquot. Store at 4℃ short term (1~2 weeks). Store at -20℃ for 2 years. Avoid freeze / thaw cycles.
Precautions Anti-Bax antibody [59M52K38] is for research use only and not for use in diagnostic or therapeutic procedures.
Background Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.

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